BDBM50150185 3-(4-Chloro-2-fluoro-phenoxy)-2-(4-methanesulfonyl-phenyl)-6-methyl-pyran-4-one::3-(4-chloro-2-fluorophenoxy)-6-methyl-2-(4-(methylsulfonyl)phenyl)-4H-pyran-4-one::CHEMBL442767

SMILES Cc1cc(=O)c(Oc2ccc(Cl)cc2F)c(o1)-c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=GMFBOPYRPYUAME-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50150185   

TargetProstaglandin G/H synthase 2(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50150185(3-(4-chloro-2-fluorophenoxy)-6-methyl-2-(4-(methyl...)
Affinity DataIC50: 200nMAssay Description:Inhibition concentration against cyclooxygenase-2 (COX-2) in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50150185(3-(4-chloro-2-fluorophenoxy)-6-methyl-2-(4-(methyl...)
Affinity DataIC50: 200nMAssay Description:Inhibition of COX2 in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50150185(3-(4-chloro-2-fluorophenoxy)-6-methyl-2-(4-(methyl...)
Affinity DataIC50: 200nMAssay Description:Inhibitory concentration for Cyclooxygenase-2 (Prostaglandin G/H synthase 2) in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50150185(3-(4-chloro-2-fluorophenoxy)-6-methyl-2-(4-(methyl...)
Affinity DataIC50: 1.88E+4nMAssay Description:Inhibition concentration against cyclooxygenase-1 (COX-1) in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50150185(3-(4-chloro-2-fluorophenoxy)-6-methyl-2-(4-(methyl...)
Affinity DataIC50: 1.88E+4nMAssay Description:Inhibitory concentration for Cyclooxygenase-1 (Prostaglandin G/H synthase 1) in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed