BDBM50150244 1-Acetyl-4-(4-but-2-ynyloxy-benzenesulfonyl)-8-methylaminomethyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL184168

SMILES CNCc1ccc2CN(C(CN(C(C)=O)c2c1)C(=O)NO)S(=O)(=O)c1ccc(OCC#CC)cc1

InChI Key InChIKey=ISBRGXFRKARDDV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50150244   

TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50150244(1-Acetyl-4-(4-but-2-ynyloxy-benzenesulfonyl)-8-met...)
Affinity DataIC50: 456nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50150244(1-Acetyl-4-(4-but-2-ynyloxy-benzenesulfonyl)-8-met...)
Affinity DataIC50: 32nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50150244(1-Acetyl-4-(4-but-2-ynyloxy-benzenesulfonyl)-8-met...)
Affinity DataIC50: 14nMAssay Description:Inhibitory activity against Tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed