BDBM50150250 4-(4-But-2-ynyloxy-benzenesulfonyl)-1-(2-methoxy-acetyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL183404

SMILES COCC(=O)N1CC(N(Cc2ccccc12)S(=O)(=O)c1ccc(OCC#CC)cc1)C(=O)NO

InChI Key InChIKey=VVCQPDVATXLSSI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50150250   

TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50150250(4-(4-But-2-ynyloxy-benzenesulfonyl)-1-(2-methoxy-a...)
Affinity DataIC50: 97nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50150250(4-(4-But-2-ynyloxy-benzenesulfonyl)-1-(2-methoxy-a...)
Affinity DataIC50: 81nMAssay Description:Inhibitory activity against Tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50150250(4-(4-But-2-ynyloxy-benzenesulfonyl)-1-(2-methoxy-a...)
Affinity DataIC50: 853nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed