BDBM50150321 CHEMBL182610::N-{3-[Benzyl-(4-phenoxy-benzyl)-amino]-2-methyl-phenyl}-methanesulfonamide

SMILES Cc1c(NS(C)(=O)=O)cccc1N(Cc1ccccc1)Cc1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=KQDPGOGGRVXIMO-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50150321   

TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150321(N-{3-[Benzyl-(4-phenoxy-benzyl)-amino]-2-methyl-ph...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of [3H]dexamethasone binding to glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150321(N-{3-[Benzyl-(4-phenoxy-benzyl)-amino]-2-methyl-ph...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150321(N-{3-[Benzyl-(4-phenoxy-benzyl)-amino]-2-methyl-ph...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150321(N-{3-[Benzyl-(4-phenoxy-benzyl)-amino]-2-methyl-ph...)
Affinity DataIC50: 235nMAssay Description:Inhibition of glucocorticoid receptor Dexamethasone response in reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150321(N-{3-[Benzyl-(4-phenoxy-benzyl)-amino]-2-methyl-ph...)
Affinity DataIC50: 240nMAssay Description:Inhibition of glucocorticoid receptor Dexamethasone responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150321(N-{3-[Benzyl-(4-phenoxy-benzyl)-amino]-2-methyl-ph...)
Affinity DataIC50: 240nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated alkaline phosphatase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150321(N-{3-[Benzyl-(4-phenoxy-benzyl)-amino]-2-methyl-ph...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated tyrosine aminotransferase in rat hepatocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed