BDBM50150475 CHEMBL3769916

SMILES Clc1cn(cn1)-c1ccc2Nc3nc(Cc4ccccc4)sc3CCc2c1

InChI Key InChIKey=AEUMVOPMWFWBKJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50150475   

TargetPresenilin-1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50150475(CHEMBL3769916)
Affinity DataIC50: 140nMAssay Description:Modulation of gamma secretase in human H4 cells assessed as inhibition of amyloid beta (1 to 42) productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details Article
PubMed