BDBM50150511 CHEMBL3770902

SMILES Cc1cn(cn1)-c1ccc2c(CCc3ccc(Cc4ccc(F)cc4)nc3C2=O)c1

InChI Key InChIKey=PIRCMEXOPRAHHM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50150511   

TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50150511(CHEMBL3770902)
Affinity DataIC50: 300nMAssay Description:Inhibition of CYP3A4 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50150511(CHEMBL3770902)
Affinity DataIC50: 1.00E+3nMAssay Description:Modulation of gamma secretase in human H4 cells assessed as inhibition of amyloid beta (1 to 42) productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details Article
PubMed