BDBM50150517 CHEMBL3770272

SMILES CC(c1ccccc1)c1ccc2c(Nc3ccc(cc3NC2=O)-n2cnc(Cl)c2)n1

InChI Key InChIKey=HSPGPMSOFQXJKN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50150517   

TargetPresenilin-1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50150517(CHEMBL3770272)
Affinity DataIC50: 200nMAssay Description:Modulation of gamma secretase in human H4 cells assessed as inhibition of amyloid beta (1 to 42) productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50150517(CHEMBL3770272)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details Article
PubMed