BDBM50150693 CHEMBL415576::methyl 2-[(2R)-2-[(2R,3S)-3-(benzyloxy)-2-{2-[(2R,3R)-2-[(2R)-2-[(2R)-2-(2-{2-[(2R)-2-{[(tert-butoxy)carbonyl]amino}-3-methylbutanamido]acetamido}-2-methylpropanamido)-3-methylbutanamido]-3-methylbutanamido]-3-methylpentanamido]-2-methylpropanamido}butanamido]-3-methylbutanamido]-2-methylpropanoate
SMILES CC[C@@H](C)[C@@H](NC(=O)[C@H](NC(=O)[C@H](NC(=O)C(C)(C)NC(=O)CNC(=O)[C@H](NC(=O)OC(C)(C)C)C(C)C)C(C)C)C(C)C)C(=O)NC(C)(C)C(=O)N[C@H]([C@H](C)OCc1ccccc1)C(=O)N[C@H](C(C)C)C(=O)NC(C)(C)C(=O)OC
InChI Key InChIKey=WXDLZEHDWRMKAW-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50150693
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Human)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibitory activity against Gamma-secretase in HeLa cells expressing APP-reporterMore data for this Ligand-Target Pair