BDBM50150697 3-Imidazo[1,2-a]pyridin-3-yl-4-[9-methyl-2-(piperidine-1-carbonyl)-1,2,3,4-tetrahydro-[1,4]diazepino[6,7,1-hi]indol-7-yl]-pyrrole-2,5-dione::CHEMBL186290

SMILES Cc1cc2CN(CCn3cc(C4=C(C(=O)NC4=O)c4cnc5ccccn45)c(c1)c23)C(=O)N1CCCCC1

InChI Key InChIKey=LQESNGDPCQOCKO-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50150697   

TargetCyclin-dependent kinase 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50150697(3-Imidazo[1,2-a]pyridin-3-yl-4-[9-methyl-2-(piperi...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human Cyclin-dependent kinase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50150697(3-Imidazo[1,2-a]pyridin-3-yl-4-[9-methyl-2-(piperi...)
Affinity DataIC50: 370nMAssay Description:Inhibition of human Protein kinase C beta 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
LigandPNGBDBM50150697(3-Imidazo[1,2-a]pyridin-3-yl-4-[9-methyl-2-(piperi...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50150697(3-Imidazo[1,2-a]pyridin-3-yl-4-[9-methyl-2-(piperi...)
Affinity DataIC50: 41nMAssay Description:Inhibition of Glycogen synthase kinase-3 beta dependent Tau protein serine-396 phosphorylation in human SY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50150697(3-Imidazo[1,2-a]pyridin-3-yl-4-[9-methyl-2-(piperi...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human Cyclin-dependent kinase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50150697(3-Imidazo[1,2-a]pyridin-3-yl-4-[9-methyl-2-(piperi...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human Akt1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50150697(3-Imidazo[1,2-a]pyridin-3-yl-4-[9-methyl-2-(piperi...)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of human Glycogen synthase kinase-3 betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50150697(3-Imidazo[1,2-a]pyridin-3-yl-4-[9-methyl-2-(piperi...)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of human TGF-beta type II receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
LigandPNGBDBM50150697(3-Imidazo[1,2-a]pyridin-3-yl-4-[9-methyl-2-(piperi...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human Protein kinase A betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed