BDBM50150772 (3-Chloro-4-fluoro-phenyl)-pyrrolo[2,1-f][1,2,4]triazin-4-yl-amine::CHEMBL185637

SMILES Fc1ccc(Nc2ncnn3cccc23)cc1Cl

InChI Key InChIKey=BCBRJDZMKPNHMU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50150772   

TargetVascular endothelial growth factor receptor 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50150772((3-Chloro-4-fluoro-phenyl)-pyrrolo[2,1-f][1,2,4]tr...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50150772((3-Chloro-4-fluoro-phenyl)-pyrrolo[2,1-f][1,2,4]tr...)
Affinity DataIC50: 110nMAssay Description:In vitro inhibition of Epidermal growth factor receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50150772((3-Chloro-4-fluoro-phenyl)-pyrrolo[2,1-f][1,2,4]tr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50150772((3-Chloro-4-fluoro-phenyl)-pyrrolo[2,1-f][1,2,4]tr...)
Affinity DataIC50: 118nMAssay Description:Inhibition of VEGFR-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed