BDBM50150831 4-[(N-Cyclohexyl-3-methylamino-pyrrolidine-1-carboximidoyl)-amino]-N-[2-(2,4-dichloro-phenyl)-ethyl]-benzamide::CHEMBL186439

SMILES CNC1CCN(C1)C(Nc1ccc(cc1)C(=O)NCCc1ccc(Cl)cc1Cl)=NC1CCCCC1

InChI Key InChIKey=VMEVITMYQPTNSR-UHFFFAOYSA-N

Data  3 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50150831   

TargetMelanocortin receptor 5(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50150831(4-[(N-Cyclohexyl-3-methylamino-pyrrolidine-1-carbo...)
Affinity DataKi:  36nMAssay Description:Inhibition of [125I]NDP-MSH binding to human Melanocortin 5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50150831(4-[(N-Cyclohexyl-3-methylamino-pyrrolidine-1-carbo...)
Affinity DataIC50: 630nMAssay Description:Inhibition of human Melanocortin 5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50150831(4-[(N-Cyclohexyl-3-methylamino-pyrrolidine-1-carbo...)
Affinity DataKi:  1.40E+3nMAssay Description:Binding affinity for human melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50150831(4-[(N-Cyclohexyl-3-methylamino-pyrrolidine-1-carbo...)
Affinity DataKi:  2.30E+3nMAssay Description:Binding affinity for human melanocortin 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50150831(4-[(N-Cyclohexyl-3-methylamino-pyrrolidine-1-carbo...)
Affinity DataEC50:  4.60E+3nMAssay Description:Agonistic activity for human Melanocortin 4 receptor as stimulated cAMP releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed