BDBM50150882 CHEMBL184971::Isoindolinone Urea derivative::isoindolinone analog 3

SMILES CC(C)OCc1ccc2n(CCCCC(=O)N(C)C)c3c4Cc5ccccc5-c4c4C(=O)NCc4c3c2c1

InChI Key InChIKey=FBRQJIGPZJLFIQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50150882   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

LigandPNGBDBM50150882(Isoindolinone Urea derivative | CHEMBL184971 | iso...)
Affinity DataIC50: 18nMpH: 7.4 T: 2°CAssay Description:The assay was using baculovirus-expressed recombinant protein kinase and biotinylated poly-Glu-Ala-Tyr substrate. HTRF is based on the proximity of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2005
Entry Details Article
PubMed