BDBM50151282 CHEMBL3770555

SMILES Cc1cnc(s1)-c1nc(C(=O)NCCCCC(=O)C(F)(F)F)c(s1)C1CC1

InChI Key InChIKey=GJSCCYDUKNGSLB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50151282   

TargetHistone deacetylase 6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50151282(CHEMBL3770555)
Affinity DataIC50: 23nMAssay Description:Inhibition of full length His6-tagged GST-fused recombinant human HDAC6 expressed in High5 insect cells using Boc-Lys (e-acetyl)-AMC as substrate aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2017
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50151282(CHEMBL3770555)
Affinity DataIC50: 27nMAssay Description:Inhibition of full length His6-tagged GST-fused recombinant human HDAC3 expressed in High5 insect cells using Ac-Lys-Tyr-Lys (e-acetyl)-AMC as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2017
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50151282(CHEMBL3770555)
Affinity DataIC50: 32nMAssay Description:Inhibition of full length His6-tagged GST-fused recombinant human HDAC4 expressed in High5 insect cells using Ac-Lys-Tyr-Lys (e-acetyl)-AMC as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2017
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50151282(CHEMBL3770555)
Affinity DataIC50: 34nMAssay Description:Inhibition of full length His6-tagged GST-fused recombinant human HDAC1 expressed in High5 insect cells using Ac-Lys-Tyr-Lys (e-acetyl)-AMC as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2017
Entry Details Article
PubMed