BDBM50151444 (1R,2R,3R,5R,6R)-2-Amino-6-fluoro-3-hydroxy-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid::CHEMBL185822

SMILES N[C@@]1([C@H]2[C@@H](C[C@H]1O)[C@]2(F)C(O)=O)C(O)=O

InChI Key InChIKey=RQMATUGEOACXDC-UHFFFAOYSA-N

Data  2 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50151444   

TargetMetabotropic glutamate receptor 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50151444((1R,2R,3R,5R,6R)-2-Amino-6-fluoro-3-hydroxy-bicycl...)
Affinity DataIC50: 476nMAssay Description:Concentration required to inhibit metabotropic glutamate receptor 2 activity of rat expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50151444((1R,2R,3R,5R,6R)-2-Amino-6-fluoro-3-hydroxy-bicycl...)
Affinity DataEC50: >1.00E+5nMAssay Description:Effective concentration for agonistic activity towards metabotropic glutamate receptor 2 of rat expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50151444((1R,2R,3R,5R,6R)-2-Amino-6-fluoro-3-hydroxy-bicycl...)
Affinity DataKi:  32.9nMAssay Description:Binding affinity towards metabotropic glutamate receptor 2 of rat expressed in CHO cells was determined by using [3H]MGS-0008More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50151444((1R,2R,3R,5R,6R)-2-Amino-6-fluoro-3-hydroxy-bicycl...)
Affinity DataKi:  67.1nMAssay Description:Binding affinity towards metabotropic glutamate receptor 3 of rat expressed in CHO cells was determined by using [3H]MGS-0008More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed