BDBM50151514 2-{4-(3-chlorophenyl)-5-[4-cyanophenyl(1-methyl-1H-5-imidazolyl)methoxymethyl]-2-oxo-1,2-dihydro-1-pyridinylmethyl}benzonitrile::CHEMBL425539

SMILES Cn1cncc1C(OCc1cn(Cc2ccccc2C#N)c(=O)cc1-c1cccc(Cl)c1)c1ccc(cc1)C#N

InChI Key InChIKey=AVUINSKBUODDHF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50151514   

LigandPNGBDBM50151514(2-{4-(3-chlorophenyl)-5-[4-cyanophenyl(1-methyl-1H...)
Affinity DataIC50: 7.70E+3nMAssay Description:inhibitory concentration needed to to reduce the bovine GGTase-catalyzed incorporation of [3H]-FPP into a biotin-linked K-ras (B) decapeptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed