BDBM50152020 3-[4-(4-Phenyl-piperazin-1-yl)-butyl]-1H-indole-5-carbonitrile::CHEMBL188835

SMILES N#Cc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccccc3)c2c1

InChI Key InChIKey=NMONVBAPWMEOIO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50152020   

LigandPNGBDBM50152020(3-[4-(4-Phenyl-piperazin-1-yl)-butyl]-1H-indole-5-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of [3H]5-HT re-uptake in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50152020(3-[4-(4-Phenyl-piperazin-1-yl)-butyl]-1H-indole-5-...)
Affinity DataIC50: 3.80nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor of rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50152020(3-[4-(4-Phenyl-piperazin-1-yl)-butyl]-1H-indole-5-...)
Affinity DataIC50: 400nMAssay Description:Inhibition of 8-OH DPAT binding to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed