BDBM50152191 Phosphoric acid 5-(4-amino-2-oxo-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester 5-(6-amino-purin-9-yl)-2-phosphonooxymethyl-tetrahydro-furan-3-yl ester::Phosphorylated dinucleotide derivative

SMILES Nc1ccn(C2CC(O)C(COP([O-])(=O)OC3CC(OC3COP([O-])([O-])=O)n3cnc4c(N)ncnc34)O2)c(=O)n1

InChI Key InChIKey=WINZRPZYASMZGV-UHFFFAOYSA-K

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50152191   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Georgia

Curated by ChEMBL
LigandPNGBDBM50152191(Phosphoric acid 5-(4-amino-2-oxo-2H-pyrimidin-1-yl...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibitory activity against 3'-processing step in wild-type HIV-1 integrase was determined using 21-mer oligonucleotide substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Georgia

Curated by ChEMBL
LigandPNGBDBM50152191(Phosphoric acid 5-(4-amino-2-oxo-2H-pyrimidin-1-yl...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibitory activity against strand transfer in wild-type HIV-1 integrase was determined using 21-mer oligonucleotide substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed