BDBM50152326 CHEMBL363008::[Hydroxy-(1-tetradecyl-pyrrolidin-3-yl)-methyl]-phosphonic acid

SMILES CCCCCCCCCCCCCCN1CCC(C1)C(=O)P(O)(O)O

InChI Key InChIKey=ZUZDTPVPNQRGSJ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50152326   

TargetSphingosine 1-phosphate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50152326([Hydroxy-(1-tetradecyl-pyrrolidin-3-yl)-methyl]-ph...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [33P]-S1P binding to human Sphingosine 1-phosphate receptor 2 expressed on CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50152326([Hydroxy-(1-tetradecyl-pyrrolidin-3-yl)-methyl]-ph...)
Affinity DataIC50: 40nMAssay Description:Inhibition of [33P]-S1P binding to human Sphingosine 1-phosphate receptor 5 expressed on CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50152326([Hydroxy-(1-tetradecyl-pyrrolidin-3-yl)-methyl]-ph...)
Affinity DataIC50: 17nMAssay Description:Inhibition of [33P]-S1P binding to human Sphingosine 1-phosphate receptor 3 expressed on CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50152326([Hydroxy-(1-tetradecyl-pyrrolidin-3-yl)-methyl]-ph...)
Affinity DataIC50: 50nMAssay Description:Inhibition of [33P]-S1P binding to human Sphingosine 1-phosphate receptor 1 expressed on CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50152326([Hydroxy-(1-tetradecyl-pyrrolidin-3-yl)-methyl]-ph...)
Affinity DataIC50: 150nMAssay Description:Inhibition of [33P]-S1P binding to human Sphingosine 1-phosphate receptor 4 expressed on CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed