BDBM50152511 CHEMBL365243::[1-(4-Benzyloxy-benzoyl)-2-methyl-1H-indol-4-yl]-acetic acid

SMILES Cc1cc2c(CC(O)=O)cccc2n1C(=O)c1ccc(OCc2ccccc2)cc1

InChI Key InChIKey=KBGBVBBZGMDNAA-UHFFFAOYSA-N

Data  5 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50152511   

TargetProstaglandin D2 receptor(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152511([1-(4-Benzyloxy-benzoyl)-2-methyl-1H-indol-4-yl]-a...)
Affinity DataIC50: 1.30E+3nMAssay Description:Effect on the increase in cAMP formation induced by PGD-2 in the presence of bovine serum albumin in CHO cells expressing mouse Prostaglandin D2 rece...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152511([1-(4-Benzyloxy-benzoyl)-2-methyl-1H-indol-4-yl]-a...)
Affinity DataKi:  60nMAssay Description:Ability to inhibit the binding of [3H]PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152511([1-(4-Benzyloxy-benzoyl)-2-methyl-1H-indol-4-yl]-a...)
Affinity DataKi:  330nMAssay Description:Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin E receptor EP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152511([1-(4-Benzyloxy-benzoyl)-2-methyl-1H-indol-4-yl]-a...)
Affinity DataKi:  1.20E+3nMAssay Description:Ability to inhibit the binding of [3H]PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin E receptor EP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152511([1-(4-Benzyloxy-benzoyl)-2-methyl-1H-indol-4-yl]-a...)
Affinity DataKi:  1.20E+3nMAssay Description:Ability to inhibit the binding of [3H]PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin E receptor EP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152511([1-(4-Benzyloxy-benzoyl)-2-methyl-1H-indol-4-yl]-a...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to inhibit the binding of [3H]PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin E receptor EP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed