BDBM50152819 3-{2-[4-((R)-3-(4-Chloro-phenyl)-2-{[(R)-oxo-(1,2,3,4-tetrahydro-isoquinolin-3-yl)-methyl]-amino}-propionyl)-piperazin-1-yl]-benzylamino}-propionic acid::CHEMBL360169

SMILES OC(=O)CCNCc1ccccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1Cc2ccccc2CN1

InChI Key InChIKey=QHORZWWWRAJLGS-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50152819   

TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50152819(3-{2-[4-((R)-3-(4-Chloro-phenyl)-2-{[(R)-oxo-(1,2,...)
Affinity DataEC50:  90nMAssay Description:Effective concentration against cAMP release in CHO cells expressing human melanocortin-4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50152819(3-{2-[4-((R)-3-(4-Chloro-phenyl)-2-{[(R)-oxo-(1,2,...)
Affinity DataKi:  490nMAssay Description:Displacement of [125I]NDP-MSH from HEK293 cells expressing human melanocortin-4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed