BDBM50153036 5-Methyl-3,4-diphenyl-isoxazole::CHEMBL365033

SMILES Cc1onc(c1-c1ccccc1)-c1ccccc1

InChI Key InChIKey=ZXIRUKJWLADSJS-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50153036   

TargetProstaglandin G/H synthase 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50153036(5-Methyl-3,4-diphenyl-isoxazole | CHEMBL365033)
Affinity DataIC50: 90nMAssay Description:In vitro inhibitory concentration against Prostaglandin G/H synthase 1 in human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50153036(5-Methyl-3,4-diphenyl-isoxazole | CHEMBL365033)
Affinity DataIC50: 2.49E+3nMAssay Description:In vitro inhibitory concentration against Prostaglandin G/H synthase 2 in human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50153036(5-Methyl-3,4-diphenyl-isoxazole | CHEMBL365033)
Affinity DataIC50: 2.49E+3nMAssay Description:Inhibition of human monocyte COX2 by whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50153036(5-Methyl-3,4-diphenyl-isoxazole | CHEMBL365033)
Affinity DataIC50: 90nMAssay Description:Inhibition of human platelet COX1 by whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Bari "Aldo Moro"

Curated by ChEMBL
LigandPNGBDBM50153036(5-Methyl-3,4-diphenyl-isoxazole | CHEMBL365033)
Affinity DataIC50: 90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50153036(5-Methyl-3,4-diphenyl-isoxazole | CHEMBL365033)
Affinity DataIC50: 2.49E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed