BDBM50153125 CHEMBL364844::{1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-2,2-dioxo-1,4-dihydro-2H-2lambda*6*-benzo[1,2,6]thiadiazin-3-yl}-acetic acid methyl ester

SMILES COC(=O)CN1Cc2ccccc2N(C2CCN(CC2)C2CCC(CC2)C(C)C)S1(=O)=O

InChI Key InChIKey=LHUZUUOHCWKFDO-UHFFFAOYSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50153125   

TargetNociceptin receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153125({1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-2,2...)
Affinity DataKi:  41nMAssay Description:Agonist activity as stimulation of [35S]-GTP-gamma binding to human Opioid receptor like 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153125({1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-2,2...)
Affinity DataEC50:  166nMAssay Description:Agonist activity as stimulation of [35S]-GTP-gamma binding to human Opioid receptor like 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153125({1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-2,2...)
Affinity DataKi:  182nMAssay Description:Inhibition of [3H]diprenorphine binding to human Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153125({1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-2,2...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of [3H]U-69593 binding to human Opioid receptor kappa 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153125({1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-2,2...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of [3H]naltrindole binding to human Opioid receptor delta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed