BDBM50153126 1-[1-(Decahydro-naphthalen-2-yl)-piperidin-4-yl]-1,3-dihydro-benzo[1,2,5]thiadiazole 2,2-dioxide::CHEMBL184646

SMILES O=S1(=O)Nc2ccccc2N1C1CCN(CC1)C1CCC2CCCCC2C1

InChI Key InChIKey=PPDCAWVGWRJLLP-UHFFFAOYSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50153126   

TargetNociceptin receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153126(1-[1-(Decahydro-naphthalen-2-yl)-piperidin-4-yl]-1...)
Affinity DataKi:  225nMAssay Description:Inhibition of [3H]nociceptin binding to human Opioid receptor like 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153126(1-[1-(Decahydro-naphthalen-2-yl)-piperidin-4-yl]-1...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of [3H]naltrindole binding to human Opioid receptor delta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153126(1-[1-(Decahydro-naphthalen-2-yl)-piperidin-4-yl]-1...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of [3H]U-69593 binding to human Opioid receptor kappa 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153126(1-[1-(Decahydro-naphthalen-2-yl)-piperidin-4-yl]-1...)
Affinity DataEC50:  3.36E+3nMAssay Description:Agonist activity as stimulation of [35S]-GTP-gamma binding to human Opioid receptor like 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153126(1-[1-(Decahydro-naphthalen-2-yl)-piperidin-4-yl]-1...)
Affinity DataKi:  5.55E+3nMAssay Description:Inhibition of [3H]diprenorphine binding to human Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed