BDBM50153131 CHEMBL185415::{1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-2,2-dioxo-1,4-dihydro-2H-2lambda*6*-benzo[1,2,6]thiadiazin-3-yl}-acetonitrile

SMILES CC(C)C1CCC(CC1)N1CCC(CC1)N1c2ccccc2CN(CC#N)S1(=O)=O

InChI Key InChIKey=DLVOUZKERQBUTP-UHFFFAOYSA-N

Data  4 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50153131   

TargetMu-type opioid receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153131({1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-2,2...)
Affinity DataKi:  25nMAssay Description:Inhibition of [3H]diprenorphine binding to human Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153131({1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-2,2...)
Affinity DataKi:  33nMAssay Description:Inhibition of [3H]nociceptin binding to human Opioid receptor like 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153131({1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-2,2...)
Affinity DataEC50:  227nMAssay Description:Agonist activity as stimulation of [35S]-GTP-gamma binding to human Opioid receptor like 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153131({1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-2,2...)
Affinity DataEC50:  344nMAssay Description:Agonist activity as stimulation of [35S]-GTP-gamma binding to human Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153131({1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-2,2...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of [3H]naltrindole binding to human Opioid receptor delta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153131({1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-2,2...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of [3H]U-69593 binding to human Opioid receptor kappa 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed