BDBM50153568 3-Benzo[1,3]dioxol-5-yl-3-({1-[3-(N''-pyridin-4-ylmethyl-guanidino)-benzoyl]-piperidine-4-carbonyl}-amino)-propionic acid::CHEMBL184397

SMILES NC(NCc1ccncc1)=Nc1cccc(c1)C(=O)N1CCC(CC1)C(=O)NC(CC(O)=O)c1ccc2OCOc2c1

InChI Key InChIKey=PYQJLWQPRHUJDF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50153568   

TargetIntegrin alpha-V/beta-3(Human)
University of Bradford

Curated by ChEMBL
LigandPNGBDBM50153568(3-Benzo[1,3]dioxol-5-yl-3-({1-[3-(N''-pyridin-4-yl...)
Affinity DataIC50: 25nMAssay Description:Antagonist activity at alphavbeta3 integrin receptor (unknown origin) by cell-free ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
University of Bradford

Curated by ChEMBL
LigandPNGBDBM50153568(3-Benzo[1,3]dioxol-5-yl-3-({1-[3-(N''-pyridin-4-yl...)
Affinity DataIC50: 25.3nMAssay Description:Inhibition of human vitronectin binding to immobilized Alpha v beta-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
University of Bradford

Curated by ChEMBL
LigandPNGBDBM50153568(3-Benzo[1,3]dioxol-5-yl-3-({1-[3-(N''-pyridin-4-yl...)
Affinity DataIC50: 56nMAssay Description:Antagonist activity at alpha2bbeta3 integrin receptor (unknown origin) by cell-free ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
University of Bradford

Curated by ChEMBL
LigandPNGBDBM50153568(3-Benzo[1,3]dioxol-5-yl-3-({1-[3-(N''-pyridin-4-yl...)
Affinity DataIC50: 56.4nMAssay Description:Inhibition of human Biotinylated Fg binding to immobilized Alpha II beta-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed