BDBM50153658 CHEMBL3775378

SMILES C[C@@H]1Cc2cc(ccc2[C@H](N1CC(C)C)c3ccc(cc3)/C=C/C(=O)O)O

InChI Key InChIKey=WHZIOQODOSOYPX-UHFFFAOYSA-N

Data  6 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50153658   

TargetEstrogen receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50153658(CHEMBL3775378)
Affinity DataIC50: 1.30nMAssay Description:Downregulation of ERalpha in human MCF7 cells incubated for 18 to 22 hrs by immunofluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50153658(CHEMBL3775378)
Affinity DataIC50: 19nMAssay Description:Displacement of fluormone ES2 from GST-tagged recombinant human ERalpha LBD after 1 hr by Lanthascreen TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
LigandPNGBDBM50153658(CHEMBL3775378)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG tail current by plate-based planar patch clamp systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50153658(CHEMBL3775378)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human recombinant mu1 opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetB2 bradykinin receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50153658(CHEMBL3775378)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant human bradykinin receptor 2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50153658(CHEMBL3775378)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of recombinant human adenosine receptor A1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed