BDBM50153809 7-ethyl-7-hydroxy-14-(4-trifluoromethylphenyl)-(7S)-7,8,11,13-tetrahydro-10H-[1,3]dioxolo[5,4-g]pyrano[3'',4'':6,7]indolizino[1,2-b]quinoline-8,11-dione::CHEMBL364360

SMILES CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4cc5OCOc5cc4c(c3Cn1c2=O)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=WLSIGMVEGURPOY-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50153809   

TargetDNA topoisomerase 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50153809(7-ethyl-7-hydroxy-14-(4-trifluoromethylphenyl)-(7S...)
Affinity DataEC50:  160nMAssay Description:Effective concentration against DNA topoisomerase IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed