BDBM50153992 4-[2-(4-Fluoro-phenyl)-6-methoxy-pyrazolo[1,5-b]pyridazin-3-yl]-benzenesulfonamide::CHEMBL365267

SMILES COc1ccc2c(c(nn2n1)-c1ccc(F)cc1)-c1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=KOFMTMMWWZKHPS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50153992   

TargetProstaglandin G/H synthase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50153992(4-[2-(4-Fluoro-phenyl)-6-methoxy-pyrazolo[1,5-b]py...)
Affinity DataIC50: 2.61E+3nMAssay Description:Inhibition of human cyclooxygenase-1 expressed in COS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50153992(4-[2-(4-Fluoro-phenyl)-6-methoxy-pyrazolo[1,5-b]py...)
Affinity DataIC50: 26nMAssay Description:Inhibition of human cyclooxygenase-2 expressed in COS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed