BDBM50154057 2-(4-Hydroxy-phenyl)-benzooxazol-5-ol::2-(4-hydroxyphenyl)benzo[d]oxazol-5-ol::CHEMBL187392

SMILES Oc1ccc(cc1)-c1nc2cc(O)ccc2o1

InChI Key InChIKey=DPAMLAKLEWYMGF-UHFFFAOYSA-N

Data  8 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50154057   

TargetEstrogen receptor beta(Mouse)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154057(2-(4-hydroxyphenyl)benzo[d]oxazol-5-ol | 2-(4-Hydr...)
Affinity DataIC50: 9.90nMAssay Description:Inhibition of [3H]17-beta-estradiol binding to mouse ER beta expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154057(2-(4-hydroxyphenyl)benzo[d]oxazol-5-ol | 2-(4-Hydr...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of [3H]17-beta-estradiol binding to rat ER beta expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154057(2-(4-hydroxyphenyl)benzo[d]oxazol-5-ol | 2-(4-Hydr...)
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibitory concentration against human ER alpha expressed in Escherichia coli was determined using [3H]17-beta-estradiol as radio ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Mouse)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154057(2-(4-hydroxyphenyl)benzo[d]oxazol-5-ol | 2-(4-Hydr...)
Affinity DataIC50: 1.63E+3nMAssay Description:Inhibition of [3H]17-beta-estradiol binding to mouse ER alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154057(2-(4-hydroxyphenyl)benzo[d]oxazol-5-ol | 2-(4-Hydr...)
Affinity DataIC50: 49nMAssay Description:Inhibitory concentration against human ER beta expressed in Escherichia coli was determined using [3H]17-beta-estradiol as radio ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154057(2-(4-hydroxyphenyl)benzo[d]oxazol-5-ol | 2-(4-Hydr...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of [3H]17-beta-estradiol binding to rat ER alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154057(2-(4-hydroxyphenyl)benzo[d]oxazol-5-ol | 2-(4-Hydr...)
Affinity DataIC50: 6nMAssay Description:Binding affinity to ERbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154057(2-(4-hydroxyphenyl)benzo[d]oxazol-5-ol | 2-(4-Hydr...)
Affinity DataIC50: 6nMAssay Description:Binding affinity to ERbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154057(2-(4-hydroxyphenyl)benzo[d]oxazol-5-ol | 2-(4-Hydr...)
Affinity DataEC50:  47nMAssay Description:Displacement of [3H]-17beta-E2 from human ERbeta LBD by solid phase competitive radio ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed