BDBM50154418 4-(1-Methyl-1H-indol-2-yl)-2,4-dioxo-butyric acid methyl ester::CHEMBL188686::Methyl 2-Hydroxy-4-(1-methyl-1H-indol-2-yl)-4-oxobut-2-enoate

SMILES COC(=O)C(=O)CC(=O)c1cc2ccccc2n1C

InChI Key InChIKey=SYCHISINKXVHFO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50154418   

TargetIntegrase(Human immunodeficiency virus type 1)
Università

Curated by ChEMBL
LigandPNGBDBM50154418(4-(1-Methyl-1H-indol-2-yl)-2,4-dioxo-butyric acid ...)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibitory concentration against HIV-1 integrase mediated strand transfer reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Università

Curated by ChEMBL
LigandPNGBDBM50154418(4-(1-Methyl-1H-indol-2-yl)-2,4-dioxo-butyric acid ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against HIV-1 integrase mediated 3' processing reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50154418(4-(1-Methyl-1H-indol-2-yl)-2,4-dioxo-butyric acid ...)
Affinity DataIC50: 2.22E+7nMAssay Description:Inhibition of Human immunodeficiency virus 1 integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article