BDBM50154441 2-(4-Chloro-phenyl)-5,6-dihydroxy-pyrimidine-4-carboxylic acid methyl ester::CHEMBL188277

SMILES COC(=O)c1nc([nH]c(=O)c1O)-c1ccc(Cl)cc1

InChI Key InChIKey=MHARIBGZGXOTCI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50154441   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50154441(2-(4-Chloro-phenyl)-5,6-dihydroxy-pyrimidine-4-car...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory concentration required to inhibit HCV RNA dependent RNA polymerase Nonstructural protein 5B in the presence of Mn2+ is determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50154441(2-(4-Chloro-phenyl)-5,6-dihydroxy-pyrimidine-4-car...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration required to inhibit HCV RNA dependent RNA polymerase Nonstructural protein 5B in the presence of Mg2+ is determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed