BDBM50154443 2-(4-Chloro-phenyl)-6-hydroxy-5-methoxy-pyrimidine-4-carboxylic acid::CHEMBL186437

SMILES COc1c(nc([nH]c1=O)-c1ccc(Cl)cc1)C(O)=O

InChI Key InChIKey=IXYIAHYFFVLMEG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50154443   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50154443(2-(4-Chloro-phenyl)-6-hydroxy-5-methoxy-pyrimidine...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory concentration required to inhibit HCV RNA dependent RNA polymerase Nonstructural protein 5B in the presence of Mg2+ is determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50154443(2-(4-Chloro-phenyl)-6-hydroxy-5-methoxy-pyrimidine...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory concentration required to inhibit HCV RNA dependent RNA polymerase Nonstructural protein 5B in the presence of Mn2+ is determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed