BDBM50154444 2-(3-Benzyloxy-phenyl)-5,6-dihydroxy-pyrimidine-4-carboxylic acid::CHEMBL188307

SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1cccc(OCc2ccccc2)c1

InChI Key InChIKey=IHENRRNKCCTTGR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50154444   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50154444(2-(3-Benzyloxy-phenyl)-5,6-dihydroxy-pyrimidine-4-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration required to inhibit HCV RNA dependent RNA polymerase Nonstructural protein 5B in the presence of Mn2+ is determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50154444(2-(3-Benzyloxy-phenyl)-5,6-dihydroxy-pyrimidine-4-...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibitory concentration required to inhibit HCV RNA dependent RNA polymerase Nonstructural protein 5B in the presence of Mg2+ is determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50154444(2-(3-Benzyloxy-phenyl)-5,6-dihydroxy-pyrimidine-4-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration required to inhibit HIV-RT is determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50154444(2-(3-Benzyloxy-phenyl)-5,6-dihydroxy-pyrimidine-4-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory concentration required to inhibit HIV-integrase is determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase I(Escherichia coli (strain K12))
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50154444(2-(3-Benzyloxy-phenyl)-5,6-dihydroxy-pyrimidine-4-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration required to inhibit Klenow DNA-dependent DNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed