BDBM50154446 5-Hydroxy-2-(3-hydroxy-phenyl)-1-methyl-6-oxo-1,6-dihydro-pyrimidine-4-carboxylic acid::CHEMBL359981

SMILES Cn1c(nc(C(O)=O)c(O)c1=O)-c1cccc(O)c1

InChI Key InChIKey=DTNSUVZNLPPFGV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50154446   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50154446(5-Hydroxy-2-(3-hydroxy-phenyl)-1-methyl-6-oxo-1,6-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration required to inhibit HCV RNA dependent RNA polymerase Nonstructural protein 5B in the presence of Mn2+ is determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50154446(5-Hydroxy-2-(3-hydroxy-phenyl)-1-methyl-6-oxo-1,6-...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibitory concentration required to inhibit HCV RNA dependent RNA polymerase Nonstructural protein 5B in the presence of Mg2+ is determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed