BDBM50155144 4-(3-Phenyl-1H-indol-2-ylmethylene)-5-pyrazin-2-yl-2,4-dihydro-pyrazol-3-one::CHEMBL365064

SMILES O=C1NN=C(\C1=C\c1[nH]c2ccccc2c1-c1ccccc1)c1cnccn1

InChI Key InChIKey=PCOZNIRSQUKGAF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50155144   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50155144(4-(3-Phenyl-1H-indol-2-ylmethylene)-5-pyrazin-2-yl...)
Affinity DataIC50: 20nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2(KDR) without DTT (dithiothreitol)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50155144(4-(3-Phenyl-1H-indol-2-ylmethylene)-5-pyrazin-2-yl...)
Affinity DataIC50: 470nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2(KDR) with DTT (dithiothreitol)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed