BDBM50155148 (Z)-4-((4-(2-(diethylamino)ethyl)-3,5-dimethyl-1H-pyrrol-2-yl)methylene)-3-(pyrazin-2-yl)-1H-pyrazol-5(4H)-one::4-[4-(2-Diethylamino-ethyl)-3,5-dimethyl-1H-pyrrol-2-ylmethylene]-5-pyrazin-2-yl-2,4-dihydro-pyrazol-3-one::CHEMBL425356

SMILES CCN(CC)CCc1c(C)[nH]c(\C=C2/C(=O)NN=C2c2cnccn2)c1C

InChI Key InChIKey=DBHHGWWEFJEXFX-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50155148   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50155148((Z)-4-((4-(2-(diethylamino)ethyl)-3,5-dimethyl-1H-...)
Affinity DataIC50: 80nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2(KDR) with DTT (dithiothreitol)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50155148((Z)-4-((4-(2-(diethylamino)ethyl)-3,5-dimethyl-1H-...)
Affinity DataIC50: 210nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2(KDR) without DTT (dithiothreitol)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50155148((Z)-4-((4-(2-(diethylamino)ethyl)-3,5-dimethyl-1H-...)
Affinity DataKi:  316nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed