BDBM50155257 CHEMBL3774606

SMILES CN1CC[C@H](CCC\C=C\c2ccccc2Cc2ccccc2)[C@H](C1)C(O)=O

InChI Key InChIKey=XBCGCXGALIGPDD-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50155257   

TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50155257(CHEMBL3774606)
Affinity DataIC50: 2.47E+4nMAssay Description:Inhibition of mouse GAT1 expressed in HEK293 cells assessed as [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA/unlabeled GABA addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2017
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50155257(CHEMBL3774606)
Affinity DataKi:  3.99E+4nMAssay Description:Displacement of NO 711 from mouse GAT1 expressed in HEK293 cell membranes after 40 mins by LC-ESI-MS-MS-based MS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2017
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50155257(CHEMBL3774606)
Affinity DataIC50: 8.49E+4nMAssay Description:Inhibition of mouse GAT3 expressed in HEK293 cells assessed as [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA/unlabeled GABA addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2017
Entry Details Article
PubMed