BDBM50155340 1-{4-[4-(2-{4-[bis(4-fluorophenyl)methyl]piperazin-1-yl}ethoxy)phenyl]but-3-yn-1-yl}-1-hydroxyurea::CHEMBL187637

SMILES NC(=O)N(O)CCC#Cc1ccc(OCCN2CCN(CC2)C(c2ccc(F)cc2)c2ccc(F)cc2)cc1

InChI Key InChIKey=NDNBZMHADGKSLT-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50155340   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50155340(1-{4-[4-(2-{4-[bis(4-fluorophenyl)methyl]piperazin...)
Affinity DataIC50: 48nMAssay Description:Inhibition of 5-lipoxygenase activity in human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50155340(1-{4-[4-(2-{4-[bis(4-fluorophenyl)methyl]piperazin...)
Affinity DataKi:  295nMAssay Description:Binding affinity towards human histamine H1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed