BDBM50155375 CHEMBL364215::N-[(R)-1-(4-Chloro-benzyl)-2-oxo-2-(4-{2-[(2-thiophen-2-yl-ethylamino)-methyl]-phenyl}-piperazin-1-yl)-ethyl]-nicotinamide

SMILES Clc1ccc(C[C@@H](NC(=O)c2cccnc2)C(=O)N2CCN(CC2)c2ccccc2CNCCc2cccs2)cc1

InChI Key InChIKey=KCOGRZRTHYZEQU-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50155375   

TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155375(N-[(R)-1-(4-Chloro-benzyl)-2-oxo-2-(4-{2-[(2-thiop...)
Affinity DataKi:  41nMAssay Description:Tested for inhibition of binding to MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155375(N-[(R)-1-(4-Chloro-benzyl)-2-oxo-2-(4-{2-[(2-thiop...)
Affinity DataKi:  730nMAssay Description:Binding affinity towards human melanocortin 5 receptor expressed in HEK 293 cells was determined by using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155375(N-[(R)-1-(4-Chloro-benzyl)-2-oxo-2-(4-{2-[(2-thiop...)
Affinity DataKi:  1.80E+3nMAssay Description:Binding affinity towards human melanocortin 3 receptor expressed in HEK 293 cells was determined by using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed