BDBM50155380 -(2R)-[2-aminoacetamido]-3-(4-chlorophenyl)propionyl-1-2-[(2-thienyl)ethylaminomethyl]phenyl piperazine::2-Amino-N-[(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-{2-[(2-thiophen-2-yl-ethylamino)-methyl]-phenyl}-piperazin-1-yl)-ethyl]-acetamide::CHEMBL390130

SMILES NCC(=O)N[C@H](Cc1ccc(Cl)cc1)C(=O)N1CCN(CC1)c1ccccc1CNCCc1cccs1

InChI Key InChIKey=YEUMEJHOKABUMX-UHFFFAOYSA-N

Data  6 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50155380   

TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155380(-(2R)-[2-aminoacetamido]-3-(4-chlorophenyl)propion...)
Affinity DataEC50:  580nMAssay Description:Agonist activity at human MC4 receptor expressed in HEK293 cells assessed as stimulation of cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155380(-(2R)-[2-aminoacetamido]-3-(4-chlorophenyl)propion...)
Affinity DataKi:  44nMAssay Description:Displacement of [125]NDP-MSH from human MC4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155380(-(2R)-[2-aminoacetamido]-3-(4-chlorophenyl)propion...)
Affinity DataKi:  44nMAssay Description:Tested for inhibition of binding to MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155380(-(2R)-[2-aminoacetamido]-3-(4-chlorophenyl)propion...)
Affinity DataKi:  990nMAssay Description:Displacement of [125]NDP-MSH from human MC5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155380(-(2R)-[2-aminoacetamido]-3-(4-chlorophenyl)propion...)
Affinity DataKi:  990nMAssay Description:Binding affinity towards human melanocortin 5 receptor expressed in HEK 293 cells was determined by using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155380(-(2R)-[2-aminoacetamido]-3-(4-chlorophenyl)propion...)
Affinity DataKi:  1.90E+3nMAssay Description:Displacement of [125]NDP-MSH from human MC3receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155380(-(2R)-[2-aminoacetamido]-3-(4-chlorophenyl)propion...)
Affinity DataKi:  1.90E+3nMAssay Description:Binding affinity towards human melanocortin 3 receptor expressed in HEK 293 cells was determined by using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed