BDBM50155461 3-(4-Iodo-phenyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid 2-fluoro-ethyl ester::CHEMBL186306

SMILES FCCOC(=O)C1C2CCC(CC1c1ccc(I)cc1)N2

InChI Key

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50155461   

TargetSodium-dependent serotonin transporter(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50155461(3-(4-Iodo-phenyl)-8-aza-bicyclo[3.2.1]octane-2-car...)
Affinity DataKi:  0.180nMAssay Description:Displacement of [3H]cyanoimiprimine from serotonin transporter of rat cerebral cortical homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50155461(3-(4-Iodo-phenyl)-8-aza-bicyclo[3.2.1]octane-2-car...)
Affinity DataKi:  0.850nMAssay Description:Displacement of [3H]CIT from dopamine transporter of rat striatal homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50155461(3-(4-Iodo-phenyl)-8-aza-bicyclo[3.2.1]octane-2-car...)
Affinity DataKi:  5nMAssay Description:Inhibition of [18F]PET binding to dopamine transporter of human brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed