BDBM50155663 3-(4-Hydroxy-piperidin-1-yl)-N-{6-[3-(4-hydroxy-piperidin-1-yl)-propionylamino]-9-oxo-9,10-dihydro-acridin-3-yl}-propionamide::CHEMBL1079899::CHEMBL365070

SMILES OC1CCN(CCC(=O)Nc2ccc3c(O)c4ccc(NC(=O)CCN5CCC(O)CC5)cc4nc3c2)CC1

InChI Key InChIKey=BYVQQPJORNGETP-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50155663   

TargetTelomerase reverse transcriptase(Human)
University of London

Curated by ChEMBL
LigandPNGBDBM50155663(CHEMBL365070 | CHEMBL1079899 | 3-(4-Hydroxy-piperi...)
Affinity DataEC50:  1.70E+3nMAssay Description:Concentration required to inhibit 50% of telomerase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
University of London

Curated by ChEMBL
LigandPNGBDBM50155663(CHEMBL365070 | CHEMBL1079899 | 3-(4-Hydroxy-piperi...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
University of London

Curated by ChEMBL
LigandPNGBDBM50155663(CHEMBL365070 | CHEMBL1079899 | 3-(4-Hydroxy-piperi...)
Affinity DataEC50:  1.70E+3nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed