BDBM50155666 3-(4-Hydroxy-piperidin-1-yl)-N-{7-[3-(4-hydroxy-piperidin-1-yl)-propionylamino]-9-oxo-9,10-dihydro-acridin-2-yl}-propionamide::CHEMBL1078525::CHEMBL365069

SMILES OC1CCN(CCC(=O)Nc2ccc3nc4ccc(NC(=O)CCN5CCC(O)CC5)cc4c(O)c3c2)CC1

InChI Key InChIKey=BKMWOFREENGXSB-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50155666   

TargetTelomerase reverse transcriptase(Human)
University of London

Curated by ChEMBL
LigandPNGBDBM50155666(CHEMBL365069 | CHEMBL1078525 | 3-(4-Hydroxy-piperi...)
Affinity DataEC50:  2.30E+3nMAssay Description:Concentration required to inhibit 50% of telomerase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
University of London

Curated by ChEMBL
LigandPNGBDBM50155666(CHEMBL365069 | CHEMBL1078525 | 3-(4-Hydroxy-piperi...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
University of London

Curated by ChEMBL
LigandPNGBDBM50155666(CHEMBL365069 | CHEMBL1078525 | 3-(4-Hydroxy-piperi...)
Affinity DataEC50:  2.30E+3nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed