BDBM50155800 CHEMBL3780686

SMILES CN(Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(=O)[C@@H]1CCN(C[C@H]1c1ccccc1)C(=O)CCN1Cc2ccccc2C[C@H](NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)C1=O

InChI Key InChIKey=MCUGZTRVJVPHRW-UHFFFAOYSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50155800   

TargetSubstance-P receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50155800(CHEMBL3780686)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]SP from human NK1 receptor transfected in CHO cells by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2017
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50155800(CHEMBL3780686)
Affinity DataKi:  3.10nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2017
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50155800(CHEMBL3780686)
Affinity DataKi:  6.70nMAssay Description:Antagonist activity against human NK1 receptor expressed in CHO-K1 cells by aequorin luminescence assay based Schild's plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2017
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50155800(CHEMBL3780686)
Affinity DataKi:  7.10nMAssay Description:Displacement of [3H]DSLET from delta opioid receptor in rat brain membrane after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2017
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50155800(CHEMBL3780686)
Affinity DataIC50: 10nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2017
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50155800(CHEMBL3780686)
Affinity DataIC50: 30nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2017
Entry Details Article
PubMed