BDBM50156089 6-Cyclohexylamino-9-((2R,3R,4S,5S)-3,4,5-trihydroxy-tetrahydro-furan-2-yl)-9H-purine-2-carbonitrile::CHEMBL365564

SMILES O[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NC3CCCCC3)nc(nc12)C#N

InChI Key InChIKey=OKAYCQSOIKKHMZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50156089   

TargetCathepsin K(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50156089(6-Cyclohexylamino-9-((2R,3R,4S,5S)-3,4,5-trihydrox...)
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration against recombinant human cathepsin K by using Z-Phe-Arg-AMC as synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50156089(6-Cyclohexylamino-9-((2R,3R,4S,5S)-3,4,5-trihydrox...)
Affinity DataIC50: 340nMAssay Description:Inhibitory concentration against recombinant human cathepsin S by using Z-Leu-Leu-Arg-AMC as synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50156089(6-Cyclohexylamino-9-((2R,3R,4S,5S)-3,4,5-trihydrox...)
Affinity DataIC50: 430nMAssay Description:Inhibitory concentration against recombinant human cathepsin L by using Z-Phe-Arg-AMC as synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed