BDBM50156092 9-Cyclopentyl-6-(2-{4-[2-(2-methoxy-ethylamino)-ethoxy]-benzyloxy}-phenylamino)-9H-purine-2-carbonitrile::CHEMBL361499

SMILES COCCNCCOc1ccc(COc2ccccc2Nc2nc(nc3n(cnc23)C2CCCC2)C#N)cc1

InChI Key InChIKey=MLAYQZHQPOWWIL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50156092   

TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50156092(9-Cyclopentyl-6-(2-{4-[2-(2-methoxy-ethylamino)-et...)
Affinity DataIC50: 71nMAssay Description:Inhibitory concentration against recombinant human cathepsin S by using Z-Leu-Leu-Arg-AMC as synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50156092(9-Cyclopentyl-6-(2-{4-[2-(2-methoxy-ethylamino)-et...)
Affinity DataIC50: 230nMAssay Description:Inhibitory concentration against recombinant human cathepsin L by using Z-Phe-Arg-AMC as synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50156092(9-Cyclopentyl-6-(2-{4-[2-(2-methoxy-ethylamino)-et...)
Affinity DataIC50: 14nMAssay Description:Inhibitory concentration against recombinant human cathepsin K by using Z-Phe-Arg-AMC as synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed