BDBM50156251 CHEMBL186676::Thiophene-2-sulfonic acid (3-{(R)-2-[(R)-2-(7-benzyloxy-1H-indol-3-yl)-1-methyl-ethylamino]-1-hydroxy-ethyl}-phenyl)-amide

SMILES C[C@H](Cc1c[nH]c2c(OCc3ccccc3)cccc12)NC[C@H](O)c1cccc(NS(=O)(=O)c2cccs2)c1

InChI Key InChIKey=DWPUALIYKUCWGW-UHFFFAOYSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50156251   

TargetBeta-2 adrenergic receptor(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50156251(Thiophene-2-sulfonic acid (3-{(R)-2-[(R)-2-(7-benz...)
Affinity DataEC50:  6.60nMAssay Description:Agonistic activity was determined by measuring cAMP accumulation in CHO cells expressing cloned human Beta-2 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50156251(Thiophene-2-sulfonic acid (3-{(R)-2-[(R)-2-(7-benz...)
Affinity DataEC50:  54nMAssay Description:Binding inhibition constant was determined by inhibition of [125I]iodocyanopindolol binding to Beta-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50156251(Thiophene-2-sulfonic acid (3-{(R)-2-[(R)-2-(7-benz...)
Affinity DataEC50:  0.760nMAssay Description:Binding inhibition constant was determined by inhibition of [125I]iodocyanopindolol binding to Beta-3 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50156251(Thiophene-2-sulfonic acid (3-{(R)-2-[(R)-2-(7-benz...)
Affinity DataEC50:  0.760nMAssay Description:Agonist activity at Homo sapiens (human) beta3 adrenoreceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50156251(Thiophene-2-sulfonic acid (3-{(R)-2-[(R)-2-(7-benz...)
Affinity DataEC50:  6.60nMAssay Description:Agonist activity at Homo sapiens (human) beta1 adrenoreceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50156251(Thiophene-2-sulfonic acid (3-{(R)-2-[(R)-2-(7-benz...)
Affinity DataEC50:  54nMAssay Description:Agonist activity at Homo sapiens (human) beta2 adrenoreceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed