BDBM50156386 CHEMBL3785354

SMILES CC1=NN(C(=O)\C1=C/c1cn(CC(O)Cn2cc(\C=C3\C(C)=NN(C3=O)c3cccc(Cl)c3)c3ccccc23)c2ccccc12)c1cccc(Cl)c1

InChI Key InChIKey=MTLCMLQSFONAJJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50156386   

TargetDihydrofolate reductase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50156386(CHEMBL3785354)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human DHFR assessed as conversion of dihydrofolic acid to tetrahydrfolic acid by enzyme immunoassay in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed