BDBM50156674 CHEMBL3793145

SMILES CCCc1c(noc1-c1nc(no1)-c1ccc(CN2CC(C2)C(O)=O)cc1)-c1ccccn1

InChI Key InChIKey=SLRXSFQHNXRKQK-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50156674   

TargetSphingosine 1-phosphate receptor 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50156674(CHEMBL3793145)
Affinity DataEC50:  0.210nMAssay Description:Agonist activity at human S1P1 receptor expressed in CHO cell membranes assessed as stimulation of [35S]GTPgamma binding incubated for 45 mins by liq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2017
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50156674(CHEMBL3793145)
Affinity DataEC50:  630nMAssay Description:Agonist activity at human S1P3 receptor expressed in EDG3-Ga15-bla HEK293T cell membranes assessed as stimulation of [35S]GTPgamma binding incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2017
Entry Details Article
PubMed