BDBM50156696 2-{[4-(2-butynyloxy)phenyl]sulfanyl}-2-cyclohexyl-N-hydroxyacetamide::CHEMBL222992

SMILES CC#CCOc1ccc(SC(C2CCCCC2)C(=O)NO)cc1

InChI Key InChIKey=ILUVAAMGYFXXGD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50156696   

LigandPNGBDBM50156696(2-{[4-(2-butynyloxy)phenyl]sulfanyl}-2-cyclohexyl-...)
Affinity DataIC50: 105nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50156696(2-{[4-(2-butynyloxy)phenyl]sulfanyl}-2-cyclohexyl-...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50156696(2-{[4-(2-butynyloxy)phenyl]sulfanyl}-2-cyclohexyl-...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50156696(2-{[4-(2-butynyloxy)phenyl]sulfanyl}-2-cyclohexyl-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed